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Central factor in signaling pathways regulated by ethylene (ET) and involved in various processes including development, plant defense, senescence, nucleotide sugar flux, and tropisms (PubMed:27694846, PubMed:28874528). Necessary for ethylene-mediated gene regulation, and for the induction of some genes by ozone. Acts downstream of ET receptors, and upstream of ethylene regulated transcription factors. Required for cytokinin-mediated processes. Seems to be implicated in cross-talk between ET, jasmonate and other pathways. Probably not involved in iron uptake (PubMed:10381874, PubMed:12953109, PubMed:14973160, PubMed:15010611, PubMed:15272873, PubMed:7770519, PubMed:9351240). Has a short half-life and undergoes rapid proteasome-mediated turnover in the absence of ethylene (PubMed:19196655). Required for ethylene-induced EIN3 stabilization via proteasomal degradation of EBF1/EBF2 proteins (PubMed:20647342). Regulates the leaf senescence induced by methyl jasmonate, ethylene and abscisic acid (Ref.17, PubMed:15010611). Required during salt stress to confer resistance (PubMed:21631530).
CKR1; ORE3
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