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Fibronectin type III domain-containing protein 5, the precursor of irisin, is a protein that is encoded by the FNDC5 gene. This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants.
1500001L03Rik; AI836596; C87088; fibronectin type III domain containing 5; fibronectin type III domain-containing protein 5; Fibronectin type III repeat-containing protein 2; Fndc5; Frcp2; Irisin; PeP; Peroxisomal protein; Pxp
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