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Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.
AW227548; Chfz-1; Dfrizzled-1; DKFZp564G072; Drosophila polarity gene (frizzled) homologue; Drosophila polarity gene homolog 1; FLJ95923; frizzled; frizzled 1; frizzled 1, seven transmembrane spanning receptor; frizzled class receptor 1; frizzled family receptor 1; frizzled homolog 1; frizzled homolog 1 (Drosophila); frizzled, Drosophila, homolog of, 1; frizzled-1; Fz receptor 1; Fz1; FZ-1; Fzd1; FzE1; hFz1; mFz1; rFz1; Wnt receptor; Xfrizzled-1
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