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          • Primary Antibodies ›
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          IL-27 p28 Antibodies

          Antibodies that detect IL-27 p28 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Neutralization. These antibodies target IL-27 p28 in Human, Mouse and Rat samples. Our IL-27 p28 polyclonal, monoclonal, recombinant... Antibodies that detect IL-27 p28 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Neutralization. These antibodies target IL-27 p28 in Human, Mouse and Rat samples. Our IL-27 p28 polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal antibodies are... Antibodies that detect IL-27 p28 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Neutralization. These antibodies target IL-27 p28 in Human, Mouse and Rat samples. Our IL-27 p28 polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse, Rat and Goat. These antibodies have been verified by Neutralization to confirm specificity to IL-27 p28. Find the IL-27 p28 antibody that fits your needs. Choose from 1 of 25 IL-27 p28 antibodies, which have been validated in experiments with 6 publications and 32 images featured in our data gallery.

          Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP,...
          Antibodies that detect IL-27 p28 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Neutralization. These antibodies target IL-27 p28 in Human, Mouse and Rat samples. Our IL-27 p28 polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse, Rat and Goat. These antibodies have been verified by Neutralization to confirm specificity to IL-27 p28. Find the IL-27 p28 antibody that fits your needs. Choose from 1 of 25 IL-27 p28 antibodies, which have been validated in experiments with 6 publications and 32 images featured in our data gallery.

          Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

          靶标信息

          IL-27, a member of the IL-12 family, is a heterodimeric protein consisting of the p40-related protein Epstein-Barr virus-induced gene 3 (EBI3) non-covalently linked to an IL-12p35-related protein, p28 (also known as IL-30). IL-27 is produced by activated APCs and mature dendritic cells. IL-27 exerts its activities on NK cells and naive CD4+ T cells; mRNA expression analysis of IL-27 receptor components (WSX-1/TCCR and gp130) suggests that IL-27 may also target other cells, including mast cells and monocytes. Binding of IL-27 to WSX-1/gp130 activates JAK1, STAT1, and STAT3 and STAT1/3 phosphorylation. WSX-1/TCCR-deficient mice develop impaired Th1 responses and are more susceptible to infection with L. monocytogenes suggesting that Th1 responses require IL-27. Although activation of WSX-1 is required for the initiation of Th1 responses, it is not necessary for maintaining Th1 responses. IL-27 alone is not able to induce the differentiation of CD4+ T cells into IFN-γ-producing cells, suggesting a role for IL-27 as an initial activator of Th1 responses. An important effect of IL-27 in initiating Th1 responses is the induction of the Th1-specific transcription factor T-bet as well as the suppression of the Th2-specific transcription factor GATA-3. T-bet plays a critical role in Th1 differentiation by its ability to maintain IL-12Rβ2 expression following CD4+ T cell activation. Recent studies indicate that IL-27 has a potent antitumor activity. In vitro, IL-27 has been found to act directly on naive CD8 cells, generating CTL with enhanced granzyme B expression. In vivo, IL-27 has been reported to augment CTL activity, inhibit tumor growth, and induce complete regression of primary and metastatic neuroblastoma tumors.

          同义词

          IL27; IL-27; IL-27 p28 subunit; IL-27 subunit alpha; Il27a; IL-27A; IL-27-A; IL27-A; IL27p28; IL-27p28; IL30; IL-30; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27; interleukin-27 subunit alpha; Interleukin-30; p28

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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          23个结果
          种属
          类型
          应用
          价格
          对比
          23个结果
          Invitrogen
          IL-27 p28 Monoclonal Antibody (MM27-7B1), PE, eBioscience™
          Invitrogen
          IL-27 p28 Monoclonal Antibody (MM27-7B1), PE, eBioscience™
          1
          种属
          Mouse
          类型
          Mouse Monoclonal
          应用
          Flow
          价格
          Special offer
          Online exclusive
          飞享价
          货号 12-7285-80

          25 µg

          Invitrogen
          IL-27 p28 Polyclonal Antibody
          Invitrogen
          IL-27 p28 Polyclonal Antibody
          高级验证
          3
          种属
          Mouse
          类型
          Goat Polyclonal
          应用
          WB IHC (P) Neu
          价格
          Special offer
          Online exclusive
          飞享价
          货号 PA5-46981

          100 µg

          Invitrogen
          IL-27 p28 Recombinant Rabbit Monoclonal Antibody (7H7L10)
          Invitrogen
          IL-27 p28 Recombinant Rabbit Monoclonal Antibody (7H7L10)
          1
          种属
          Human
          类型
          Rabbit Recombinant Monoclonal
          应用
          WB
          价格
          Special offer
          Online exclusive
          飞享价
          货号 701073

          100 µg

          Invitrogen
          IL-27 p28 Monoclonal Antibody (3D1p28), eFluor™ 660, eBioscience™
          Invitrogen
          IL-27 p28 Monoclonal Antibody (3D1p28), eFluor™ 660, eBioscience™
          1
          种属
          Human
          类型
          Mouse Monoclonal
          应用
          Flow
          价格
          Special offer
          Online exclusive
          飞享价
          货号 50-8277-42

          100 Tests

          Invitrogen
          IL-27 p28 Monoclonal Antibody (MM27-7B1), Functional Grade, eBioscience™
          Invitrogen
          IL-27 p28 Monoclonal Antibody (MM27-7B1), Functional Grade, eBioscience™
          种属
          Mouse
          类型
          Mouse Monoclonal
          应用
          Neu Functional
          价格
          Special offer
          Online exclusive
          飞享价
          货号 16-7285-85

          500 µg

          Invitrogen
          IL-27 p28 Recombinant Superclonal™ Antibody (7HCLC)
          Invitrogen
          IL-27 p28 Recombinant Superclonal™ Antibody (7HCLC)
          1
          种属
          Human
          类型
          Rabbit Recombinant Superclonal
          应用
          WB
          价格
          Special offer
          Online exclusive
          飞享价
          货号 710175

          100 µg

          Invitrogen
          IL-27 p28 Monoclonal Antibody (234205)
          Invitrogen
          IL-27 p28 Monoclonal Antibody (234205)
          1
          种属
          Mouse
          类型
          Rat Monoclonal
          应用
          WB Flow
          价格
          Special offer
          Online exclusive
          飞享价
          货号 MA5-61050

          500 µg

          Invitrogen
          IL-27 p28 Monoclonal Antibody (744015)
          Invitrogen
          IL-27 p28 Monoclonal Antibody (744015)
          1
          种属
          Mouse
          类型
          Rat Monoclonal
          应用
          WB
          价格
          Special offer
          Online exclusive
          飞享价
          货号 MA5-61816

          100 µg

          Invitrogen
          IL-27 p28 Polyclonal Antibody
          Invitrogen
          IL-27 p28 Polyclonal Antibody
          3
          种属
          Human Mouse
          类型
          Rabbit Polyclonal
          应用
          WB ICC/IF
          价格
          Special offer
          Online exclusive
          飞享价
          货号 PA5-20240

          100 µg

          Invitrogen
          IL-27 p28 Polyclonal Antibody
          Invitrogen
          IL-27 p28 Polyclonal Antibody
          2
          种属
          Human Mouse
          类型
          Rabbit Polyclonal
          应用
          WB
          价格
          Special offer
          Online exclusive
          飞享价
          货号 PA5-20241

          100 µg

          Invitrogen
          IL-27 p28 Polyclonal Antibody
          Invitrogen
          IL-27 p28 Polyclonal Antibody
          2
          种属
          Human
          类型
          Rabbit Polyclonal
          应用
          WB IHC (P)
          价格
          Special offer
          Online exclusive
          飞享价
          货号 PA5-78661

          100 µL

          Invitrogen
          IL-27 p28 Polyclonal Antibody
          Invitrogen
          IL-27 p28 Polyclonal Antibody
          1
          种属
          Human Mouse
          类型
          Rabbit Polyclonal
          应用
          WB
          价格
          Special offer
          Online exclusive
          飞享价
          货号 PA1-24498

          50 µg

          Invitrogen
          IL-27 p28 Polyclonal Antibody
          Invitrogen
          IL-27 p28 Polyclonal Antibody
          1
          种属
          Human Mouse
          类型
          Rabbit Polyclonal
          应用
          WB
          价格
          Special offer
          Online exclusive
          飞享价
          货号 PA1-41055

          100 µg

          Invitrogen
          IL-27 p28 Polyclonal Antibody
          Invitrogen
          IL-27 p28 Polyclonal Antibody
          1
          种属
          Human Mouse Rat
          类型
          Rabbit Polyclonal
          应用
          WB IHC (PFA)
          价格
          Special offer
          Online exclusive
          飞享价
          货号 PA5-115411

          100 µL

          Invitrogen
          IL-27 p28 Polyclonal Antibody
          Invitrogen
          IL-27 p28 Polyclonal Antibody
          1
          种属
          Mouse Rat
          类型
          Rabbit Polyclonal
          应用
          WB ELISA
          价格
          Special offer
          Online exclusive
          飞享价
          货号 PA5-79492

          100 µg

          Invitrogen
          IL-27 p28 Polyclonal Antibody
          Invitrogen
          IL-27 p28 Polyclonal Antibody
          1
          种属
          Human
          类型
          Rabbit Polyclonal
          应用
          WB ELISA
          价格
          Special offer
          Online exclusive
          飞享价
          货号 PA5-80727

          100 µL

          Abnova
          IL27 Monoclonal Antibody (3F12)
          Abnova
          IL27 Monoclonal Antibody (3F12)
          3
          种属
          Human
          类型
          Mouse Monoclonal
          应用
          WB ELISA IP
          价格
          Special offer
          Online exclusive
          飞享价
          货号 H00246778-M01

          100 µg

          Invitrogen
          IL-27 p28 Recombinant Rabbit Monoclonal Antibody (001)
          Invitrogen
          IL-27 p28 Recombinant Rabbit Monoclonal Antibody (001)
          种属
          Human
          类型
          Rabbit Recombinant Monoclonal
          应用
          ELISA
          价格
          Special offer
          Online exclusive
          飞享价
          货号 MA5-30825

          100 µL

          Abnova
          IL27 Polyclonal Antibody, MaxPab™
          Abnova
          IL27 Polyclonal Antibody, MaxPab™
          1
          种属
          Human
          类型
          Rabbit Polyclonal
          应用
          WB
          价格
          Special offer
          Online exclusive
          飞享价
          货号 H00246778-D01P

          100 µg

          Rockland
          IL-27/p28 Monoclonal Antibody (3H12.F10)
          Rockland
          IL-27/p28 Monoclonal Antibody (3H12.F10)
          种属
          Mouse
          类型
          Rat Monoclonal
          应用
          WB Flow ELISA
          价格
          Special offer
          Online exclusive
          飞享价
          货号 210-501-B54
          Rockland
          IL-27/p28 Polyclonal Antibody
          Rockland
          IL-27/p28 Polyclonal Antibody
          种属
          Mouse
          类型
          Rabbit Polyclonal
          应用
          WB ELISA
          价格
          Special offer
          Online exclusive
          飞享价
          货号 210-401-B54

          100 µg

          Rockland
          IL-27/p28 Polyclonal Antibody, HRP
          Rockland
          IL-27/p28 Polyclonal Antibody, HRP
          种属
          Mouse
          类型
          Rabbit Polyclonal
          应用
          WB IHC ELISA
          价格
          Special offer
          Online exclusive
          飞享价
          货号 210-403-B54

          100 µg

          Rockland
          IL-27/p28 Polyclonal Antibody, Biotin
          Rockland
          IL-27/p28 Polyclonal Antibody, Biotin
          种属
          Mouse
          类型
          Rabbit Polyclonal
          应用
          WB IHC ELISA
          价格
          Special offer
          Online exclusive
          飞享价
          货号 210-406-B54

          100 µg

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