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Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.
2400003C14Rik; AW536298; fb16b04; hIST1; hypothetical protein LOC321460; hypothetical protein LOC508900; increased sodium tolerance 1 homolog; increased sodium tolerance 1 homolog (yeast); IST1; IST1 factor associated with ESCRT-III; IST1 homolog; IST1, endosomal sorting complex required for transport-III component; IST1, ESCRT-III associated factor; IST1-like protein; Kiaa0174; KIAA0174-like protein; MAPK activating protein PM28; MGC117220; mKIAA0174; OLC1; overexpressed in lung cancer 1; pm28; putative MAPK-activating protein PM28; RGD1307799; wu:fb16b04; wu:fi89e07; zgc:55671
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