靶标信息
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex.
同义词
5430421N21Rik; hair keratin; Hair keratin K2.10; hard keratin, type II, 3; HB3; Hb-3; hHb3; K83; keratin 83; keratin 83, type II; keratin 84; keratin complex 2, basic, gene 25; keratin type II; keratin, hair, basic, 3; keratin, type II cuticular Hb3; keratin, type II cuticular Hb3; keratin, type II microfibrillar, component 7C; keratin, type II microfibrillar, component 7C; keratin-83; KRT83; KRTHB3; RIKEN cDNA 5430421N21 gene; type II hair keratin; type II hair keratin Hb3; Type-II keratin Kb23