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This gene encodes a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. Two transcripts variants encoding distinct isoforms have been identified for this gene.
bLhx3b; CPHD3; DKFZp762A2013; Homeobox protein LIM-3; homeobox protein P-LIM; lhx3; Lhx3b; LIM homeo box protein 3; LIM homeobox 3; LIM homeobox protein; LIM homeobox protein 3; LIM homeodomain 3; LIM homeodomain 3 protein b isoform; LIM homeodomain box protein 3; LIM homeodomain protein 3b; LIM/homeobox protein Lhx3; LIM/homeodomain protein LHX3; lim3; Lim-3; LOW QUALITY PROTEIN: LIM/homeobox protein Lhx3; M2-LHX3; mLIM3; mLim-3; Plim; P-LIM
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