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LIAS belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis.The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
2900022L22Rik; 4933425M12Rik; 7a5ex; C77512; HAMAP-Rule:MF_03123}; HGCLAS; HUSSY-01; hypothetical protein MGC66080; LAS; LIAS; LIAS protein; LIP1; Lipoate synthase; lipoate synthase {ECO:0000255; lipoic acid synthase; lipoic acid synthase {ECO:0000255; lipoic acid synthetase; lipoic acid synthetase isoform 1 precursor; lipoyl synthase, mitochondrial; lipoyl synthase, mitochondrial {ECO:0000255; Lipoyl synthase, mitochondrial-like protein; lip-syn; lip-syn {ECO:0000255; LS; LS {ECO:0000255; MGC23245; mLip1; PDHLD; zgc:66080
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