Search Thermo Fisher Scientific
The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), like the related protein LRRFIP1, was identified in a yeast two-hybrid system through binding to the LRR domain of human FLI. It can activate the Wnt signaling pathway in cultured cells and is thought to be a component of the Wnt signaling pathway that modulates Wnt signaling through interactions with Disheveled to increase the cellular levels and transcription activity of beta-catenin. LRRFIP2 has recently been characterized as a positive regulator of the TLR4 signaling pathway for activating NF-kappa-B during the early host response to LPS stimulation through binding to the TLR adaptor protein MyD88, and that this interaction with MyD88 is governed by phosphorylation of specific residues in LRRFIP2.
5133400F20Rik; AI850587; HUFI-2; leucine rich repeat (in FLII) interacting protein 2; leucine-rich repeat flightless-interactin protein 2-like protein; leucine-rich repeat flightless-interacting protein 2; LRR binding FLII interacting protein 2; LRR FLII-interacting protein 2; LRRFIP2
100 µg
100 µg
100 µg
100 µL
50 µg
100 µL
100 µL