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MARK2 is a serine/threonine protein kinase involved in the control of cell polarity and microtubule stability. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1. These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be coexpressed in a number of selected cell lines and tissue samples. The human EMK1 was shown to be encoded by a single mRNA ubiquitously expressed.
ELKL motif kinase; ELKL motif kinase 1; Emk; EMK1; EMK-1; MAP/microtubule affinity regulating kinase 2; MAP/microtubule affinity-regulating kinase 2; MARK2; mark2 {ECO:0000312; MGC99619; microtubule affinity regulating kinase 2; OTTHUMP00000218338; OTTHUMP00000218339; OTTHUMP00000218340; OTTHUMP00000218343; Par-1; PAR1 homolog; PAR1 homolog b; Par1b; Par-1b; RGD:708483}; Ser/Thr protein kinase PAR-1B; serine/threonine kinase; serine/threonine protein kinase EMK; serine/threonine-protein kinase MARK2; testicular tissue protein Li 117
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