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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p.
1810030E20Rik; 2610028L11Rik; 39S ribosomal protein L48, mitochondrial; CGI-118; D4Ertd786e; HSPC290; L48mt; MGC13323; mitochondrial 39S ribosomal protein L48-like protein; Mitochondrial large ribosomal subunit protein mL48; mitochondrial ribosomal protein L48; Mrpl48; MRP-L48; Unknown (protein for MGC:133957)
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