Search Thermo Fisher Scientific
Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380). Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs (PubMed:12477380). [UniProt]
2410012F02Rik; AI118225; exo-N4-amino; PAO; Paox; Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N1-acetyl-spermine/spermidine oxidase; polyamine oxidase; polyamine oxidase (exo-N4-amino); polyamine oxidase (exo-N4-amino) isoform 1; putative GTP-binding protein; UNQ1923/PRO4398
100 µL
400 µL
100 µL
50 µg
100 µL