Antibodies that detect PIK3R6 can be used in several scientific applications, including Western Blot, ELISA, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. These antibodies target PIK3R6 in Human, Mouse and Rat samples. Our PIK3R6 polyclonal and monoclonal antibodies...Antibodies that detect PIK3R6 can be used in several scientific applications, including Western Blot, ELISA, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. These antibodies target PIK3R6 in Human, Mouse and Rat samples. Our PIK3R6 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find...Antibodies that detect PIK3R6 can be used in several scientific applications, including Western Blot, ELISA, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. These antibodies target PIK3R6 in Human, Mouse and Rat samples. Our PIK3R6 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the PIK3R6 antibody that fits your needs. Choose from 1 of 8 PIK3R6 antibodies, which have been validated in experiments with 1 publication and 8 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot...
Antibodies that detect PIK3R6 can be used in several scientific applications, including Western Blot, ELISA, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. These antibodies target PIK3R6 in Human, Mouse and Rat samples. Our PIK3R6 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the PIK3R6 antibody that fits your needs. Choose from 1 of 8 PIK3R6 antibodies, which have been validated in experiments with 1 publication and 8 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
p87PIKAP (p87 PI3K adapter protein), also known as PIK3R6 (phosphoinositide-3-kinase, regulatory subunit 6), p84 or HsT41028, is a 754 amino acid cytoplasmic protein that functions as a regulatory subunit of the PI 3-kinase p110 complex. Expressed in heart, dendritic cells, macrophages and neutrophils, p87PIKAP drives PI 3-kinase p110 activation, interacts with PDE3B and is thought to cause the two proteins to form a scaffolding interaction. The gene encoding p87PIKAP maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1, 200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
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