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PTGR1 encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants.
12-HD; 15-oxoprostaglandin 13-reductase; 2510002C21Rik; ADRAB-F; D3T-inducible gene 1 protein; Dig1; DIG-1; Dithiolethione-inducible gene 1 protein; dithiolethione-inducible gene-1; FLJ99229; leukotriene B4 12-hydroxydehydrogenase; leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase; LTB4; LTB4DH; MGC34943; NADP-dependent leukotriene B4 12-hydroxydehydrogenase; PGR; PGR1; PRG-1; Prostaglandin reductase 1; PTGR1; unnamed protein product; Zadh3; zinc binding alcohol dehydrogenase domain containing 3
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