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SBK1 novel serine/threonine kinase or SH3 domain binding kinase 1 is structurally related to a Xenopus gastrula-specific protein kinase, Pk9.7 which possessing a consensus sequence for an SH3-binding domain from developing rat brain. SBK1 plays an important role in signal-transduction pathways related to the control of brain development. SBK1 may predict a broad cellular function, and its dysregulated in certain cancers suggests an involvement of the protein in the pathogenesis of human cancers. May be involved in signal-transduction pathways related to the control of brain development. Target protein is a serine/threonine protein kinase gene expressed predominantly in developing brain.
SBK; SBK1; Serine/threonine-protein kinase SBK1; SH3 domain binding kinase 1; SH3-binding domain kinase 1; SH3-binding kinase 1
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