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This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
1300013M05Rik; Alpha-tocopherol-associated protein; C22orf6; KIAA1186; KIAA1658; SEC14 like lipid binding 2; SEC14L2; SEC14-like 2; SEC14-like 2 (S. cerevisiae); SEC14-like lipid binding 2; SEC14-like protein 2; SEC14-like protein 2-like; SPF; squalene transfer protein; Supernatant protein factor; TAP; TAP1; tocopherol-associated protein; tocopherol-associated protein 1
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