SERPINB3/SERPINB4 Antibodies

Antibodies that detect SERPINB3/SERPINB4 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA and Immunocytochemistry. These antibodies target SERPINB3/SERPINB4 in Human, Mouse, Porcine and Rat samples. Our SERPINB3/SERPINB4... Antibodies that detect SERPINB3/SERPINB4 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA and Immunocytochemistry. These antibodies target SERPINB3/SERPINB4 in Human, Mouse, Porcine and Rat samples. Our SERPINB3/SERPINB4 polyclonal and monoclonal antibodies are... Antibodies that detect SERPINB3/SERPINB4 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA and Immunocytochemistry. These antibodies target SERPINB3/SERPINB4 in Human, Mouse, Porcine and Rat samples. Our SERPINB3/SERPINB4 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the SERPINB3/SERPINB4 antibody that fits your needs. Choose from 1 of 6 SERPINB3/SERPINB4 antibodies, which have been validated in experiments with 11 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the... Antibodies that detect SERPINB3/SERPINB4 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA and Immunocytochemistry. These antibodies target SERPINB3/SERPINB4 in Human, Mouse, Porcine and Rat samples. Our SERPINB3/SERPINB4 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the SERPINB3/SERPINB4 antibody that fits your needs. Choose from 1 of 6 SERPINB3/SERPINB4 antibodies, which have been validated in experiments with 11 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase. In 1985, Dr. Jim Travis and Dr. R.W. Carrell designated an emerging family of serine protease inhibitors as the serpin fam-ily, which share homology in both primary amino acid sequence and tertiary structure. Serpins contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. Serine proteases bind to this substrate mimic in a 1:1 stoichiometric fashion and become catalytically inactive. Aberrant ex-pression of serpin family members can contribute to a number of conditions, including emphysema (a-1 antitrypsin deficiency), fatal bleeding (elastase to thrombin specificity) and thrombosis (antithrombin deficiency), and are indicators of cancer stage phenotypes (circulating levels of squamous cell carcinoma antigen, known as SCCA1, increase in advancing stages of some cervical, lung, esophageal and head and neck cancers). Human chromosome position 18q21.3 contains a cluster of serpins, including a tandem duplication of the SCCA gene, plasminogen activator inhibitor type 2, and maspin. SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma.

Synonyms

1110001H02Rik; 1110013A16Rik; HsT1196; LEUPIN; Peptidase inhibitor 11; PI11; PI-11; protease inhibitor (leucine-serpin); protein T4-A; RGD1562868; SCC; SCCA; SCCA1; SCCA-1; SCCA2; SCCA-2; SCCA2/SCCA1 fusion protein; SCCA-PD; serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3A; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4; serine peptidase inhibitor, clade B, member 3A; serine protease inhibitor B3; serpin B3; Serpin B4; serpin family B member 3; serpin family B member 4; serpin peptidase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 4; Serpinb3; Serpinb3a; SERPINB4; spb3; Sqn5; Squamous cell carcinoma antigen 1; squamous cell carcinoma antigen 2; SSCA1; T4-A

SERPINB3/SERPINB4 Antibodies

Target Information

Synonyms

Custom Antibody Service

Performance Guarantee

We're here to help

Your items have has been added!