SIGIRR Antibodies

Antibodies that detect SIGIRR can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target SIGIRR in Human, Mouse and Rat samples. Our SIGIRR polyclonal, recombinant monoclonal and... Antibodies that detect SIGIRR can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target SIGIRR in Human, Mouse and Rat samples. Our SIGIRR polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse,... Antibodies that detect SIGIRR can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target SIGIRR in Human, Mouse and Rat samples. Our SIGIRR polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse, Goat and Rat. Find the SIGIRR antibody that fits your needs. Choose from 1 of 15 SIGIRR antibodies, which have been validated in experiments with 3 publications and 20 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody... Antibodies that detect SIGIRR can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target SIGIRR in Human, Mouse and Rat samples. Our SIGIRR polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse, Goat and Rat. Find the SIGIRR antibody that fits your needs. Choose from 1 of 15 SIGIRR antibodies, which have been validated in experiments with 3 publications and 20 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

SIGIRR (single Ig IL-1R-related molecule) is a novel member of the interleukin 1 receptor (IL-1R) superfamily. Although it shows the typical conserved motifs that characterize the IL-1R and Toll superfamily, it is structurally and functionally distinct from both. SIGIRR has only one Ig domain in its extracellular portion whereas the IL-1R family contains three Ig folds. An unusually long cytoplasmic domain is reminiscent of the structure of drosophila Toll, yet the SIGIRR peptide sequence is more closely related to IL-1RI. A chimera, in which the SIGIRR intracellular domain was fused to the IL-1R extracellular domain, did not activate NFkappaB unlike similar fusion proteins of other IL-1R related molecules. Phylogenetic data that suggest that the plasma membrane protein SIGIRR is a close functional relative of MyD88 in mammals.

同义词

AI256711; IL-1R8; MGC110992; Sigirr; single Ig and TIR domain containing; single Ig IL-1 receptor related protein; single Ig IL-1-related receptor; Single Ig IL-1R-related molecule; single Ig IL-1R-related protein; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; single immunoglobulin domain IL1R1 related; single immunoglobulin domain-containing IL1R-related protein; TIR8; Toll/interleukin-1 receptor 8; UNQ301/PRO342

SIGIRR Antibodies

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