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Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.
4931400A14Rik; AW554188; KIAA0650; mKIAA0650; MommeD1; RGD1307234; SMC hinge domain containing 1; SMC hinge domain-containing protein 1; Smchd1; structural maintenance of chromosomes flexible hinge domain containing 1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
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