SOCS1 Antibodies

Antibodies that detect SOCS1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target SOCS1 in Human, Mouse, Rat and Non-human primate samples. Our SOCS1 polyclonal,... Antibodies that detect SOCS1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target SOCS1 in Human, Mouse, Rat and Non-human primate samples. Our SOCS1 polyclonal, recombinant monoclonal and monoclonal... Antibodies that detect SOCS1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target SOCS1 in Human, Mouse, Rat and Non-human primate samples. Our SOCS1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Goat and Mouse. Find the SOCS1 antibody that fits your needs. Choose from 1 of 21 SOCS1 antibodies, which have been validated in experiments with 22 publications and 51 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the... Antibodies that detect SOCS1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target SOCS1 in Human, Mouse, Rat and Non-human primate samples. Our SOCS1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Goat and Mouse. Find the SOCS1 antibody that fits your needs. Choose from 1 of 21 SOCS1 antibodies, which have been validated in experiments with 22 publications and 51 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

The Suppressor of cytokine signaling (SOCS) and cytokine-inducible SH2 proteins are a family of intracellular proteins which regulate the immune cell responses to cytokines. SOCS1 acts to suppress dendritic cell (DC) as well as T cell hyperactivation following cytokine signaling by inhibiting JAK tyrosine kinase, a kinase necessary for type I and II cytokine receptors to initiate signaling, by directly binding to the catalytic domain of the kinase. SOCS1 also possesses E3 ubiquitin protein ligase activity that results in the polyubiquitination of its target proteins and subsequent degradation by the proteosome. It is through this method that SOCS1 negatively regulates signaling by Toll-like receptors TLR2 and TLR4 by mediating the degradation of the TLR signaling adaptor protein TIRAP.

同义词

CIS1; Cish1; Cish7; cytokine inducible SH2-containing protein 1; cytokine inducible SH2-containing protein 7; cytokine-inducible SH2 protein 1; JAB; JAK binding protein; JAK2-binding protein; JAK-binding protein; Socs1; SOCS-1; SSI1; SSI-1; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; Suppressor of cytokine signaling 1; Tec-interacting protein 3; TIP3; TIP-3

SOCS1 Antibodies

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