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TBRG1 acts as a growth inhibitor. It can activate TP53/p53, cause G1 arrest and collaborate with CDKN2A to restrict proliferation, but it does not require either protein to inhibit DNA synthesis. TBRG1 redistributes CDKN2A into the nucleoplasm, and is involved in maintaining chromosomal stability.
AA408552; AA409675; mFLJ00213; Niam; Nuclear interactor of ARF and Mdm2; Tb-5; Tbrg1; transforming growth factor beta regulated gene 1; transforming growth factor beta regulator 1
100 µL
100 µL