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This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
BB107417; bHLHe34; Class E basic helix-loop-helix protein 34; hTFEC-L; mTFEC; rTFEC; TCFEC; TFEC; TFE-C; TFECL; TFEC-L; Transcription factor EC; Transcription factor EC-like
100 µg
100 µL
100 µg
100 µg
100 µg