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Transmembrane protein 123, or Tmem123, is a single-pass type I membrane protein and belongs to the CD164 family. Tmem123 acts as a novel marker for DC maturation. DCs are also known as professional antigen-presenting cells. It is reported that the Tmem123 molecule may be closely associated with the cell surface expression of CD40. It was also reported previously that Tmem123 protein may also be responsible for oncotic cell death, which is characterized by cell swelling, organelle swelling, vacuolization, increased membrane permeability and cell adhesion.
2310075C12Rik; KCT3; KCT-3; keratinocytes associated transmembrane protein 3; keratinocytes-associated transmembrane protein 3; Porimin; PORMIN; pro oncosis receptor inducing membrane injury; pro-oncosis receptor inducing membrane injury; PSEC0111; RGD1305625; serine/threonine-rich receptor; TMEM123; Transmembrane protein 123; UNQ641/PRO1271
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