TRRAP Antibodies

Antibodies that detect TRRAP can be used in several scientific applications, including Western Blot, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry and ChIP. These antibodies target TRRAP in Human, Mouse, Rat, Non-human primate and Xenopus laevis samples. Our TRRAP... Antibodies that detect TRRAP can be used in several scientific applications, including Western Blot, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry and ChIP. These antibodies target TRRAP in Human, Mouse, Rat, Non-human primate and Xenopus laevis samples. Our TRRAP polyclonal antibodies are... Antibodies that detect TRRAP can be used in several scientific applications, including Western Blot, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry and ChIP. These antibodies target TRRAP in Human, Mouse, Rat, Non-human primate and Xenopus laevis samples. Our TRRAP polyclonal antibodies are developed in Rabbit. Find the TRRAP antibody that fits your needs. Choose from 1 of 8 TRRAP antibodies, which have been validated in experiments with 15 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the... Antibodies that detect TRRAP can be used in several scientific applications, including Western Blot, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry and ChIP. These antibodies target TRRAP in Human, Mouse, Rat, Non-human primate and Xenopus laevis samples. Our TRRAP polyclonal antibodies are developed in Rabbit. Find the TRRAP antibody that fits your needs. Choose from 1 of 8 TRRAP antibodies, which have been validated in experiments with 15 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

TRRAP is an adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. Component of the NuA4 histone acetyltransferase complex which is responsible for acetylation of nucleosomal histones H4 and H2A. TRRAP plays a central role in MYC transcription activation, and also participates in cell transformation by MYC is required for p53/TP53-, E2F1- and E2F4-mediated transcription activation and is also involved in transcription activation mediated by the adenovirus E1A, a viral oncoprotein that deregulates transcription of key genes. TRRAP probably acts by linking transcription factors such as E1A, MYC or E2F1 to HAT complexes such as STAGA thereby allowing transcription activation, however, it is probably not required in the steps following histone acetylation in processes of transcription activation. TRRAP may be required for the mitotic checkpoint and normal cell cycle progression. TRRAP is a component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.

同义词

350/400 kDa PCAF-associated factor; AI481500; OTTHUMP00000197294; OTTHUMP00000197295; PAF350/400; PAF400; STAF40; Tra1; Tra1 homolog; transactivation/transformation-domain associated protein; transformation/transcription domain associated protein; transformation/transcription domain-associated protein; TR-AP; TRRAP

TRRAP Antibodies

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