Antibodies that detect TXK can be used in several scientific applications, including Western Blot, ELISA, Immunocytochemistry and Immunohistochemistry. These antibodies target TXK in Human, Rat and Mouse samples. Our TXK polyclonal and monoclonal antibodies are developed in Rabbit, Mouse...Antibodies that detect TXK can be used in several scientific applications, including Western Blot, ELISA, Immunocytochemistry and Immunohistochemistry. These antibodies target TXK in Human, Rat and Mouse samples. Our TXK polyclonal and monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the TXK antibody that fits...Antibodies that detect TXK can be used in several scientific applications, including Western Blot, ELISA, Immunocytochemistry and Immunohistochemistry. These antibodies target TXK in Human, Rat and Mouse samples. Our TXK polyclonal and monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the TXK antibody that fits your needs. Choose from 1 of 15 TXK antibodies, which have been validated in experiments with 2 publications and 25 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re...
Antibodies that detect TXK can be used in several scientific applications, including Western Blot, ELISA, Immunocytochemistry and Immunohistochemistry. These antibodies target TXK in Human, Rat and Mouse samples. Our TXK polyclonal and monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the TXK antibody that fits your needs. Choose from 1 of 15 TXK antibodies, which have been validated in experiments with 2 publications and 25 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
TXK, along with the close relatives BMS, ITK, and BTK, signal downstream of antigen receptors and other types of receptors. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini. Four alternatively spliced forms of Tec are found to be expressed broadly in cells of hematopoietic lineage and hepatocytes. The Emt gene product associates with CD28 and becomes activated subsequent to CD28 ligation. Btk is necessary for proper B cell development, and mutations in the gene encoding Btk have been associated with families suffering from X-linked agammaglobulinemia, also referred to as Bruton's disease. The Bmx protein shares a high degree of homology with Btk and seems to be expressed at highest levels in the heart. Txk expression is T cell-specific, while expression of the Drosophila Tec homolog, Dsrc28C, is developmentally regulated.
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