Product References
GM-CSF impairs erythropoiesis by disrupting erythroblastic island formation via macrophages.
Journal of translational medicine
Cao W,Fan W,Wang F,Zhang Y,Wu G,Shi X,Shi JX,Gao F,Yan M,Guo R,Li Y,Li W,Du C,Jiang Z
Published figure using Phospho-STAT5 (Tyr694) monoclonal antibody (Product # 12-9010-42) in Flow Cytometry
Mon Jan 03 00:00:00 EST 2022
GM-CSF impairs erythropoiesis by disrupting erythroblastic island formation via macrophages.
Journal of translational medicine
Cao W,Fan W,Wang F,Zhang Y,Wu G,Shi X,Shi JX,Gao F,Yan M,Guo R,Li Y,Li W,Du C,Jiang Z
Published figure using Phospho-STAT5 (Tyr694) monoclonal antibody (Product # 12-9010-42) in Flow Cytometry
Mon Jan 03 00:00:00 EST 2022
Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ.
Aging cell
Webb LMC,Fra-Bido S,Innocentin S,Matheson LS,Attaf N,Bignon A,Novarino J,Fazilleau N,Linterman MA
12-9010-42 was used in Flow Cytometry to show increased formation of Tfh precursors (pre-Tfh) but no associated increase in germinal centre (GC)-Tfh cells in aged mice, suggesting age-driven promotion of only early Tfh cell differentiation.
Fri Jan 01 00:00:00 EST 2021
Aged neutrophils form mitochondria-dependent vital NETs to promote breast cancer lung metastasis.
Journal for immunotherapy of cancer
Yang C,Wang Z,Li L,Zhang Z,Jin X,Wu P,Sun S,Pan J,Su K,Jia F,Zhang L,Wang H,Yu X,Shao X,Wang K,Qiu F,Yan J,Huang J
12-9010-42 was used in Flow Cytometry to investigate the existence and biological function of a rarely delved subset of neutrophils, named as tumor-associated aged neutrophils (Naged, CXCR4+CD62Llow), involved in premetastatic niche formation during breast cancer metastasis.
Fri Oct 01 00:00:00 EDT 2021
Aged neutrophils form mitochondria-dependent vital NETs to promote breast cancer lung metastasis.
Journal for immunotherapy of cancer
Yang C,Wang Z,Li L,Zhang Z,Jin X,Wu P,Sun S,Pan J,Su K,Jia F,Zhang L,Wang H,Yu X,Shao X,Wang K,Qiu F,Yan J,Huang J
12-9010-42 was used in Flow Cytometry to investigate the existence and biological function of a rarely delved subset of neutrophils, named as tumor-associated aged neutrophils (Naged, CXCR4+CD62Llow), involved in premetastatic niche formation during breast cancer metastasis.
Fri Oct 01 00:00:00 EDT 2021
Long-Term Programming of CD8 T Cell Immunity by Perinatal Exposure to Glucocorticoids.
Cell
Hong JY,Lim J,Carvalho F,Cho JY,Vaidyanathan B,Yu S,Annicelli C,Ip WKE,Medzhitov R
12-9010 was used in Flow cytometry/Cell sorting to demonstrate that perinatal stress can have long-term consequences on CD8 T cell immunity by altering HPA axis activity.
Thu Mar 05 00:00:00 EST 2020
ILC3 deficiency and generalized ILC abnormalities in DOCK8-deficient patients.
Allergy
Eken A,Cansever M,Okus FZ,Erdem S,Nain E,Azizoglu ZB,Haliloglu Y,Karakukcu M,Ozcan A,Devecioglu O,Aksu G,Arikan Ayyildiz Z,Topal E,Karakoc Aydiner E,Kiykim A,Metin A,Cipe F,Kaya A,Artac H,Reisli I,Guner SN,Uygun V,Karasu G,Dönmez Altuntas H,Canatan H,Oukka M,Ozen A,Chatila TA,Keles S,Baris S,Unal E,Patiroglu T
12-9010 was used in Flow cytometry/Cell sorting to sought to test whether DOCK8 is required for the function and maintenance of ILC subsets in humans.
Wed Apr 01 00:00:00 EDT 2020
SRC-3 Functions as a Coactivator of T-bet by Regulating the Maturation and Antitumor Activity of Natural Killer Cells.
Cancer immunology research
Hu M,Lu Y,Qi Y,Zhang Z,Wang S,Xu Y,Chen F,Tang Y,Chen S,Chen M,Du C,Shen M,Wang F,Su Y,Deng Y,Wang J
12-9010-42 was used in Flow Cytometry to study the role of SRC-3 as a coactivator of T-bet in natural killer-cell biology and indicate that targeting SRC-3 may be a promising strategy to increase the tumor surveillance function of natural killer cells.
Tue Sep 01 00:00:00 EDT 2020
Novel cytokine-antibody fusion protein, N-820, to enhance the functions of ex vivo expanded natural killer cells against Burkitt lymphoma.
Journal for immunotherapy of cancer
Chu Y,Nayyar G,Kham Su N,Rosenblum JM,Soon-Shiong P,Lee J,Safrit JT,Barth M,Lee D,Cairo MS
12-9010 was used in Flow cytometry/Cell sorting to provide the rationale for the development of a clinical trial of N-820 alone or in combination with endogenous or ex vivo expanded NK cells in patients with CD20+ B-NHL failing prior rituximab containing chemoimmunotherapy regimens.
Thu Oct 01 00:00:00 EDT 2020
Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation.
eLife
Ferrao RD,Wallweber HJ,Lupardus PJ
Published figure using Phospho-STAT5 (Tyr694) monoclonal antibody (Product # 12-9010-42) in Flow Cytometry
Wed Jul 25 00:00:00 EDT 2018
CISH promoter polymorphism effects on T cell cytokine receptor signaling and type 1 diabetes susceptibility.
Molecular and cellular pediatrics
Seyfarth J,Ahlert H,Rosenbauer J,Baechle C,Roden M,Holl RW,Mayatepek E,Meissner T,Jacobsen M
12-9010 was used in Flow cytometry/Cell sorting to analyzed allele frequencies of three CISH SNPs (i.e., rs809451, rs414171, rs2239751) in a study of T1D patients (n = 260, onset age 5 years, duration > 10 years).
Tue Feb 06 00:00:00 EST 2018
Aberrant plasma IL-7 and soluble IL-7 receptor levels indicate impaired T-cell response to IL-7 in human tuberculosis.
PLoS pathogens
Lundtoft C,Afum-Adjei Awuah A,Rimpler J,Harling K,Nausch N,Kohns M,Adankwah E,Lang F,Olbrich L,Mayatepek E,Owusu-Dabo E,Jacobsen M
Thu Jun 01 00:00:00 EDT 2017
Erythropoietin enhances Kupffer cell number and activity in the challenged liver.
Scientific reports
Gilboa D,Haim-Ohana Y,Deshet-Unger N,Ben-Califa N,Hiram-Bab S,Reuveni D,Zigmond E,Gassmann M,Gabet Y,Varol C,Neumann D
Published figure using Phospho-STAT5 (Tyr694) monoclonal antibody (Product # 12-9010-42) in Flow Cytometry
Mon Sep 04 00:00:00 EDT 2017
Environmentally relevant concentrations of arsenite and monomethylarsonous acid inhibit IL-7/STAT5 cytokine signaling pathways in mouse CD3+CD4-CD8- double negative thymus cells.
Toxicology letters
Xu H,Lauer FT,Liu KJ,Hudson LG,Burchiel SW
12-9010 was used in Western Blotting to suggest that arsenic at environmentally-relevant doses suppresses early T-cell development through inhibition of IL-7 signaling.
Fri Apr 15 00:00:00 EDT 2016
Environmentally relevant concentrations of arsenite and monomethylarsonous acid inhibit IL-7/STAT5 cytokine signaling pathways in mouse CD3+CD4-CD8- double negative thymus cells.
Toxicology letters
Xu H,Lauer FT,Liu KJ,Hudson LG,Burchiel SW
12-9010 was used in Western Blotting to suggest that arsenic at environmentally-relevant doses suppresses early T-cell development through inhibition of IL-7 signaling.
Fri Apr 15 00:00:00 EDT 2016
Monomethylarsonous acid (MMA+3) Inhibits IL-7 Signaling in Mouse Pre-B Cells.
Toxicological sciences : an official journal of the Society of Toxicology
Ezeh PC,Xu H,Lauer FT,Liu KJ,Hudson LG,Burchiel SW
Published figure using Phospho-STAT5 (Tyr694) monoclonal antibody (Product # 12-9010-42) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
Expression and function of hematopoiesis-stimulating factor receptors on the GPI- and GPI+ hematopoietic stem cells of patients with paroxysmal nocturnal hemoglobinuria/aplastic anemia syndrome.
Experimental and therapeutic medicine
Fu R,Ding SX,Liu YI,Li LJ,Liu H,Wang HL,Zhang T,Shao ZH
Published figure using Phospho-STAT5 (Tyr694) monoclonal antibody (Product # 12-9010-42) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using Phospho-STAT5 (Tyr694) monoclonal antibody (Product # 12-9010-42) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
Combination of imatinib with CXCR4 antagonist BKT140 overcomes the protective effect of stroma and targets CML in vitro and in vivo.
Molecular cancer therapeutics
Beider K,Darash-Yahana M,Blaier O,Koren-Michowitz M,Abraham M,Wald H,Wald O,Galun E,Eizenberg O,Peled A,Nagler A
12-9010 was used in Flow cytometry/Cell sorting to indicate the importance of CXCR4/CXCL12 axis in CML growth and CML-BM stroma interaction.
Thu May 01 00:00:00 EDT 2014