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Invitrogen
14-3-3 theta Polyclonal Antibody
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14-3-3 theta Antibody (PA5-29421) in IHC (P)
14-3-3 theta Polyclonal Antibody detects 14-3-3 theta protein at cytoplasm and nucleus on Cal27 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Cal27 xenograft.14-3-3 theta Polyclonal Antibody (Product # PA5-29421) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-29421
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human 14-3-3 theta. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.98 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: 293T, A431, HeLa, HepG2, Mouse brain.
Predicted reactivity: Mouse (99%), Rat (99%), Rabbit (99%), Chicken (98%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 14-3-3 protein T-cell; 14-3-3 protein tau; 14-3-3 protein theta; 14-3-3 tau; 14-3-3 theta; OTTHUMP00000165887; Protein HS1; protein tau; protein, theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
基因别名: 14-3-3; 1C5; 2700028P07Rik; AA409740; AU021156; HS1; R74690; YWHAQ
UniProt ID: (Human) P27348, (Mouse) P68254
Entrez Gene ID: (Human) 10971, (Mouse) 22630
protein targeting
small GTPase mediated signal transduction
substantia nigra development
negative regulation of ion transmembrane transport
negative regulation of transcription, DNA-templated
membrane organization
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
signal transduction
