Product References
Multi-level remodelling of chromatin underlying activation of human T cells.
Scientific reports
Bediaga NG,Coughlan HD,Johanson TM,Garnham AL,Naselli G,Schröder J,Fearnley LG,Bandala-Sanchez E,Allan RS,Smyth GK,Harrison LC
Published figure using TCR alpha/beta monoclonal antibody (Product # 17-9986-42) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Viable bacterial colonization is highly limited in the human intestine in utero.
Nature medicine
Rackaityte E,Halkias J,Fukui EM,Mendoza VF,Hayzelden C,Crawford ED,Fujimura KE,Burt TD,Lynch SV
Published figure using TCR alpha/beta monoclonal antibody (Product # 17-9986-42) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
γδ T-cell Receptors Derived from Breast Cancer-Infiltrating T Lymphocytes Mediate Antitumor Reactivity.
Cancer immunology research
Janssen A,Villacorta Hidalgo J,Beringer DX,van Dooremalen S,Fernando F,van Diest E,Terrizi AR,Bronsert P,Kock S,Schmitt-Gräff A,Werner M,Heise K,Follo M,Straetemans T,Sebestyen Z,Chudakov DM,Kasatskaya SA,Frenkel FE,Ravens S,Spierings E,Prinz I,Küppers R,Malkovsky M,Fisch P,Kuball J
17-9986 was used in Flow cytometry/Cell sorting to describe molecular and functional analyses of T-cell receptors from tumor-infiltrating T lymphocytes that were in direct contact with tumor cells in breast cancer lesions from archival material.
Wed Apr 01 00:00:00 EDT 2020
CD161 contributes to prenatal immune suppression of IFNγ-producing PLZF+ T cells.
The Journal of clinical investigation
Halkias J,Rackaityte E,Hillman SL,Aran D,Mendoza VF,Marshall LR,MacKenzie TC,Burt TD
Published figure using TCR alpha/beta monoclonal antibody (Product # 17-9986-42) in Flow Cytometry
Thu May 30 00:00:00 EDT 2019
Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity.
The Journal of clinical investigation
Randzavola LO,Strege K,Juzans M,Asano Y,Stinchcombe JC,Gawden-Bone CM,Seaman MN,Kuijpers TW,Griffiths GM
17-9986-42 was used in Flow cytometry/Cell sorting to show that loss of actin-related protein complex 1B led to loss of CD8 cytotoxic T lymphocytes cytotoxicity, with the defect arising at 2 different levels.
Mon Dec 02 00:00:00 EST 2019
miR-34a: a new player in the regulation of T cell function by modulation of NF-κB signaling.
Cell death & disease
Hart M,Walch-Rückheim B,Friedmann KS,Rheinheimer S,Tänzer T,Glombitza B,Sester M,Lenhof HP,Hoth M,Schwarz EC,Keller A,Meese E
17-9986 was used in Flow cytometry/Cell sorting to identify miR-34a as a central regulator in T cells.
Fri Jan 18 00:00:00 EST 2019
Patients with CD3G mutations reveal a role for human CD3γ in Treg diversity and suppressive function.
Blood
Rowe JH,Delmonte OM,Keles S,Stadinski BD,Dobbs AK,Henderson LA,Yamazaki Y,Allende LM,Bonilla FA,Gonzalez-Granado LI,Celikbilek Celik S,Guner SN,Kapakli H,Yee C,Pai SY,Huseby ES,Reisli I,Regueiro JR,Notarangelo LD
17-9986 was used in Flow cytometry/Cell sorting to investigate abnormalities of T-cell repertoire and function in patients with genetic defects in CD3G associated with autoimmunity.
Thu May 24 00:00:00 EDT 2018
GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR.
Frontiers in immunology
Straetemans T,Kierkels GJJ,Doorn R,Jansen K,Heijhuurs S,Dos Santos JM,van Muyden ADD,Vie H,Clemenceau B,Raymakers R,de Witte M,Sebestyén Z,Kuball J
17-9986 was used in Flow cytometry/Cell sorting to report on release criteria and the stability of TEG001 drug substance and TEG001 drug product.
Fri Jul 26 00:00:00 EDT 2019
A High Frequency of HIV-Specific Circulating Follicular Helper T Cells Is Associated with Preserved Memory B Cell Responses in HIV Controllers.
mBio
Claireaux M,Galperin M,Benati D,Nouël A,Mukhopadhyay M,Klingler J,de Truchis P,Zucman D,Hendou S,Boufassa F,Moog C,Lambotte O,Chakrabarti LA
17-9986 was used in Flow cytometry/Cell sorting to suggest that T follicular help may contribute to HIV control and highlight the need for inducing such help in HIV vaccine strategies that aim at eliciting persistent B cell responses.
Tue May 08 00:00:00 EDT 2018
DNA Vaccination by Electroporation Amplifies Broadly Cross-Restricted Public TCR Clonotypes Shared with HIV Controllers.
Journal of immunology (Baltimore, Md. : 1950)
Mukhopadhyay M,Galperin M,Patgaonkar M,Vasan S,Ho DD,Nouël A,Claireaux M,Benati D,Lambotte O,Huang Y,Chakrabarti LA
17-9986 was used in Flow cytometry/Cell sorting to provide the first proof-of-concept that clonotypic analysis may be used as a tool to monitor the quality of vaccine-induced responses and modulate these toward "controller-like" responses.
Wed Nov 15 00:00:00 EST 2017
IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2.
Nature communications
Jandl C,Liu SM,Cañete PF,Warren J,Hughes WE,Vogelzang A,Webster K,Craig ME,Uzel G,Dent A,Stepensky P,Keller B,Warnatz K,Sprent J,King C
17-9986 was used in Flow cytometry/Cell sorting to identify a mechanism by which IL-21 reinforces humoural immunity by influencing the phenotype of T follicular cells to limit their expansion.
Fri Mar 17 00:00:00 EDT 2017
Evidence for Resident Memory T Cells in Rasmussen Encephalitis.
Frontiers in immunology
Owens GC,Chang JW,Huynh MN,Chirwa T,Vinters HV,Mathern GW
17-9986 was used in Flow cytometry/Cell sorting to demonstrate that a cellular immune response to an as yet unidentified antigen(s) occurs at an early stage of Rasmussen encephalitis.
Fri Mar 04 00:00:00 EST 2016
CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy.
Oncotarget
Komdeur FL,Wouters MC,Workel HH,Tijans AM,Terwindt AL,Brunekreeft KL,Plat A,Klip HG,Eggink FA,Leffers N,Helfrich W,Samplonius DF,Bremer E,Wisman GB,Daemen T,Duiker EW,Hollema H,Nijman HW,de Bruyn M
17998642 was used in flow cytometry to define the contribution of CD103+ tumor-infiltrating lymphocytes to high-grade serous epithelial ovarian cancer
Tue Nov 15 00:00:00 EST 2016
DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency.
Human molecular genetics
Volk T,Pannicke U,Reisli I,Bulashevska A,Ritter J,Björkman A,Schäffer AA,Fliegauf M,Sayar EH,Salzer U,Fisch P,Pfeifer D,Di Virgilio M,Cao H,Yang F,Zimmermann K,Keles S,Caliskaner Z,Güner SÜ,Schindler D,Hammarström L,Rizzi M,Hummel M,Pan-Hammarström Q,Schwarz K,Grimbacher B
17-9986 was used in Flow cytometry/Cell sorting to investigate the range of phenotypes associated with DCLRE1C (ARTEMIS) mutations in humans.
Sun Dec 20 00:00:00 EST 2015
Human IgE(+) B cells are derived from T cell-dependent and T cell-independent pathways.
The Journal of allergy and clinical immunology
Berkowska MA,Heeringa JJ,Hajdarbegovic E,van der Burg M,Thio HB,van Hagen PM,Boon L,Orfao A,van Dongen JJ,van Zelm MC
17-9986 was used in Flow cytometry/Cell sorting to provide new insights into the pathogenesis of IgE-mediated diseases which could help to accurately monitor IgE(+) B cells in patients undergoing anti-IgE treatment.
Mon Sep 01 00:00:00 EDT 2014
Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist.
mAbs
Thaventhiran T,Alhumeed N,Yeang HX,Sethu S,Downey JS,Alghanem AF,Olayanju A,Smith EL,Cross MJ,Webb SD,Williams DP,Bristow A,Ball C,Stebbings R,Sathish JG
17-9986 was used in Flow cytometry/Cell sorting to understand the underlying molecular mechanisms of T-cell activation in response to TGN1412-like CD28 superagonist, showing that failure to upregulate the inhibitory PD-1 cell surface receptor is part of this mechanism.
Mon Aug 24 00:00:00 EDT 2015