Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Rockland
5-caC Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
5-caC Antibody (200-401-X50) in ICC/IF
Immunofluorescence results of Rabbit anti-5-Carboxylcytosine antibody. Tissue: 293T cells (mock), transfected with catalytically inactive FLAG-tagged C-terminal domain (Tet1 mC), or transfected with mouse FLAG-tagged wild-type (Tet1 CD). Antigen retrieval: not required. Primary antibody: anti-5-Carboxylcytosine antibody at 1:500 for 1 hr at RT. Secondary antibody: rabbit anti-FLAG antibody at 1:10,000 for 45 min at RT. Staining: 5-caC antibody as (red) fluorescent signal, DAPI (blue), FLAG (in green).
产品信息
200-401-X50
应用
建议稀释比
已发表文章
产品规格
种属反应
Chemical
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-5caC Antibody was produced in rabbits by repeated immunizations with 5-carboxylcytosine (5caC).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2, with 30% glycerol
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
5-carboxylcytosine is the final oxidized derivative of 5-methylcytosine, a type of DNA methylation. 5-methylcytosine is oxidized to 5-hydroxymethylcytosine which is then oxidized to 5-formylcytosine and later to 5-carboxylcytosine. These oxidations are catalyzed by the Ten-Eleven Translocation (TET) enzyme family. 5-carboxylcytosine has been shown to cause reduced fidelity of RNA Polymerase II. Decreased levels of 5-hydroxymethylcytosine has been found in some cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
