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Proteintech
NAPSA Monoclonal Antibody (1H7F2)
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产品信息
60259-2-IG
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1H7F2
抗原
NAPSA Fusion Protein Ag9721 (1-420 aa encoded by BC017842)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSPPPLLQP LLLLLPLLNV EPSGATLIRI PLHRVQPGRR TLNLLRGWRE PAELPKLGAP SPGDKPIFVP LSNYRDVQYF GEIGLGTPPQ NFTVAFDTGS SNLWVPSRRC HFFSVPCWLH HRFDPKASSS FQANGTKFAI QYGTGRVDGI LSEDKLTIGG IKGASVIFGE ALWEPSLVFA FAHFDGILGL GFPILSVEGV RPPMDVLVEQ GLLDKPVFSF YLNRDPEEPD GGELVLGGSD PAHYIPPLTF VPVTVPAYWQ IHMERVKVGP GLTLCAKGCA AILDTGTSLI TGPTEEIRAL HAAIGGIPLL AGEYIILCSE IPKLPAVSFL LGGVWFNLTA HDYVIQTTRN GVRLCLSGFQ ALDVPPPAGP FWILGDVFLG TYVAVFDRGD MKSSARVGLA RARTRGADLG WGETAQAQFP G (1-420 aa encoded by BC017842)
靶标信息
Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: asp 4; ASP4; Aspartyl protease 4; kidney-derived aspartic protease-like protein; Napsin-1; Napsin-A; pronapsin A; TA01/TA02
基因别名: KAP; Kdap; NAP1; NAPA; NAPSA; SNAPA
UniProt ID: (Human) O96009
Entrez Gene ID: (Human) 9476
