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Proteintech
GOT1 Monoclonal Antibody (5A12E10)
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产品信息
60317-1-IG
应用
建议稀释比
已发表文章
产品规格
种属反应
Chicken,
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
5A12E10
抗原
GOT1 Fusion Protein Ag7012 (1-413 aa encoded by BC000498)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MAPPSVFAE VPQAQPVLVF KLTADFREDP DPRKVNLGVG AYRTDDCHPW VLPVVKKVEQ KIANDNSLNH EYLPILGLAE FRSCASRLAL GDDSPALKEK RVGGVQSLGG TGALRIGADF LARWYNGTNN KNTPVYVSSP TWENHNAVFS AAGFKDIRSY RYWDAEKRGL DLQGFLNDLE NAPEFSIVVL HACAHNPTGI DPTPEQWKQI ASVMKHRFLF PFFDSAYQGF ASGNLERDAW AIRYFVSEGF EFFCAQSFSK NFGLYNERVG NLTVVGKEPE SILQVLSQME KIVRITWSNP PAQGARIVAS TLSNPELFEE WTGNVKTMAD RILTMRSELR ARLEALKTPG TWNHITDQIG MFSFTGLNPK QVEYLVNEKH IYLLPSGRIN VSGLTTKNLD YVATSIHEAV TKIQ (1-413 aa encoded by BC000498)
靶标信息
GOT1 is a glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: aspartate aminotransferase 1; Aspartate aminotransferase, cytoplasmic; aspartate transaminase 1; cAspAT; cCAT; Cysteine aminotransferase, cytoplasmic; Cysteine transaminase, cytoplasmic; cytosolic aspartate aminotransferase; Glutamate oxaloacetate transaminase 1; glutamate oxaloacetate transaminase 1, soluble; glutamic-oxaloacetic transaminase 1, soluble; glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1); growth-inhibiting protein 18; testis secretory sperm-binding protein Li 196a; Transaminase A; unnamed protein product
基因别名: AI789014; Aspat; AST1; ASTQTL1; cAspAT; cCAT; Gaspat; GIG18; Got-1; GOT1
UniProt ID: (Human) P17174, (Chicken) P00504, (Rat) P13221, (Mouse) P05201
Entrez Gene ID: (Human) 2805, (Chicken) 396261, (Rat) 24401, (Mouse) 14718
L-aspartate:2-oxoglutarate aminotransferase activity
phosphatidylserine decarboxylase activity
pyridoxal phosphate binding
carboxylic acid binding
identical protein binding
L-cysteine:2-oxoglutarate aminotransferase activity
L-phenylalanine:2-oxoglutarate aminotransferase activity
catalytic activity
transaminase activity
transferase activity
transaminase
gluconeogenesis
2-oxoglutarate metabolic process
oxaloacetate metabolic process
glycerol biosynthetic process
aspartate metabolic process
aspartate biosynthetic process
aspartate catabolic process
glutamate metabolic process
Notch signaling pathway
cellular amino acid biosynthetic process
glutamate catabolic process to aspartate
glutamate catabolic process to 2-oxoglutarate
cellular response to insulin stimulus
response to glucocorticoid
fatty acid homeostasis
cellular amino acid metabolic process
dicarboxylic acid metabolic process
biosynthetic process
