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Proteintech
HSP90 Monoclonal Antibody (3F11C1)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
60318-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Published species
Human,
Monkey,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
3F11C1
Immunogen
HSP90 Fusion Protein Ag3826 (287-638 aa encoded by BC023006)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: YLNFIRGVV DSEDLPLNIS REMLQQSKIL KVIRKNLVKK CLELFTELAE DKENYKKFYE QFSKNIKLGI HEDSQNRKKL SELLRYYTSA SGDEMVSLKD YCTRMKENQK HIYYITGETK DQVANSAFVE RLRKHGLEVI YMIEPIDEYC VQQLKEFEGK TLVSVTKEGL ELPEDEEEKK KQEEKKTKFE NLCKIMKDIL EKKVEKVVVS NRLVTSPCCI VTSTYGWTAN MERIMKAQAL RDNSTMGYMA AKKHLEINPD HSIIETLRQK AEADKNDKSV KDLVILLYET ALLSSGFSLE DPQTHANRIY RMIKLGLGID EDDPTADDTS AAVTEEMPPL EGDDDTSRME EVD (287-638 aa encoded by BC023006)
Target Information
HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 and mitochondria (Chen et al., 2005 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 90-kDa heat shock protein; ATHS83; AtHsp90-1; ATHSP90.1; F6N7.13; F6N7_13; Heat shock 84 kDa; Heat shock 86 kDa; heat shock 90kD protein 1, beta; heat shock 90kDa protein 1, beta; Heat shock protein; heat shock protein 1, alpha; heat shock protein 1, beta; HEAT SHOCK PROTEIN 81-1; HEAT SHOCK PROTEIN 83; heat shock protein 86; HEAT SHOCK PROTEIN 90-1; heat shock protein 90.1; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein 90kDa alpha (cytosolic), class B member 1; Heat shock protein family C member 1; Heat shock protein family C member 3; Heat shock protein HSP 90-alpha; Heat shock protein HSP 90-beta; heat shock protein, 1; heat shock protein, 84 kDa 1; heat shock protein, 86 kDa 1; heat shock protein, 89 kDa; HSP; HSP 84; HSP 86; HSP 90; HSP81-1; HSP81.1; HSP83; HSP84; HSP86; LAP-2; Lipopolysaccharide-associated protein 2; Renal carcinoma antigen NY-REN-38; retinal degeneration slow protein; TSTA; Tumor-specific transplantation 84 kDa antigen; Tumor-specific transplantation 86 kDa antigen
Gene Aliases: 86kDa; 89kDa; 90kDa; AL022974; AL024080; AL024147; C81438; hsp4; Hsp84; Hsp84-1; Hsp86; Hsp86-1; Hsp89; HSP90; HSP90-BETA; HSP90A; HSP90AA1; HSP90AB1; HSP90B; HSPC1; HSPC2; HSPC3; HSPCA; HSPCB
UniProt ID: (Pig) O02705, (Mouse) P07901, (Rat) P82995, (Mouse) P11499, (Rat) P34058
Entrez Gene ID: (Pig) 397028, (Pig) 396742, (Mouse) 15519, (Rat) 299331, (Mouse) 15516, (Rat) 301252
nucleotide binding
UTP binding
CTP binding
mRNA binding
protein binding
ATP binding
GTP binding
ATPase activity
sulfonylurea receptor binding
protein kinase binding
protein phosphatase binding
MHC class II protein complex binding
nitric-oxide synthase regulator activity
TPR domain binding
dATP binding
identical protein binding
protein homodimerization activity
ion channel binding
poly(A) RNA binding
GTPase binding
Rho GDP-dissociation inhibitor binding
unfolded protein binding
double-stranded RNA binding
kinase binding
Hsp90 family chaperone
neuron migration
protein folding
nitric oxide biosynthetic process
response to stress
response to unfolded protein
positive regulation of lamellipodium assembly
positive regulation of protein import into nucleus, translocation
protein refolding
protein import into mitochondrial outer membrane
positive regulation of nitric oxide biosynthetic process
positive regulation of cytotoxic T cell differentiation
positive regulation of cell size
regulation of catalytic activity
chaperone-mediated protein complex assembly
skeletal muscle contraction
response to heat
response to salt stress
cardiac muscle cell apoptotic process
response to estrogen
positive regulation of cardiac muscle contraction
placenta development
virion attachment to host cell
positive regulation of protein binding
negative regulation of neuron apoptotic process
cellular response to interleukin-4
positive regulation of protein serine/threonine kinase activity
fibril organization
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of interferon-gamma-mediated signaling pathway
regulation of type I interferon-mediated signaling pathway
cellular response to organic cyclic compound
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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