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Proteintech
Sestrin2 Monoclonal Antibody (1A1A4)
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产品信息
66297-1-IG
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Pig,
Rat
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1A1A4
抗原
Sestrin 2 Fusion Protein Ag20638 (132-480 aa encoded by BC013304)
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: HMAEFLQTG GDPEWLLGLH RAPEKLRKLS EINKLLAHRP WLITKEHIQA LLKTGEHTWS LAELIQALVL LTHCHSLSSF VFGCGILPEG DADGSPAPQA PTPPSEQSSP PSRDPLNNSG GFESARDVEA LMERMQQLQE SLLRDEGTSQ EEMESRFELE KSESLLVTPS ADILEPSPHP DMLCFVEDPT FGYEDFTRRG AQAPPTFRAQ DYTWEDHGYS LIQRLYPEGG QLLDEKFQAA YSLTYNTIAM HSGVDTSVLR RAIWNYIHCV FGIRYDDYDY GEVNQLLERN LKVYIKTVAC YPEKTTRRMY NLFWRHFRHS EKVHVNLLLL EARMQAALLY ALRAITRYMT (132-480 aa encoded by BC013304)
靶标信息
This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: hypoxia induced gene 95; hypoxia-induced; Hypoxia-induced gene; Sestrin-2
基因别名: HI95; RGD1566319; SES2; SESN2; SEST2
UniProt ID: (Human) P58004
Entrez Gene ID: (Pig) 100620966, (Human) 83667, (Rat) 502988
regulation of protein phosphorylation
fatty acid beta-oxidation
autophagy
response to glucose
positive regulation of macroautophagy
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
mitochondrial DNA metabolic process
response to insulin
cellular response to oxidative stress
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
protein kinase B signaling
glucose import
triglyceride homeostasis
cellular response to amino acid stimulus
cellular response to leucine
reactive oxygen species metabolic process
regulation of gluconeogenesis involved in cellular glucose homeostasis
cellular oxidant detoxification
positive regulation of protein localization to nucleus
regulation of response to reactive oxygen species
negative regulation of translation in response to endoplasmic reticulum stress
negative regulation of TORC1 signaling
regulation of cAMP-dependent protein kinase activity
mitochondrion organization
glucose homeostasis
