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Proteintech
CCT4 Monoclonal Antibody (3C6A6)
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CCT4 Antibody (67455-1-IG) in WB
Various lysates were subjected to SDS PAGE followed by western blot with 67455-1-Ig (CCT4 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control.
产品信息
67455-1-IG
产品规格
种属反应
Human,
Mouse,
Pig,
Rabbit
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
3C6A6
抗原
Recombinant protein
偶联物
形式
Liquid
纯化类型
Protein G
保存液
PBS with 50% glycerol
内含物
0.1% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: SVVIIAGSLL DSCTKLLQKG IHPTIISESF QKALEKGIEI LTDMSRPVEL SDRETLLNSA TTSLNSKVVS QYSSLLSPMS VNAVMKVIDP ATATSVDLRD IKIVKKLGGT IDDCELVEGL VLTQKVSNSG ITRVEKAKIG LIQFCLSAPK TDMDNQIVVS DYAQMDRVLR EERAYILNLV KQIKKTGCNV LLIQKSILRD ALSDLALHFL NKMKIMVIKD IEREDIEFIC KTIGTKPVAH IDQFTADMLG SAELAEEVNL NGSGKLLKIT GCASPGKTVT IVVRGSNKLV IEEAERSIHD
靶标信息
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A45; CCT-delta; Chaperonin containing T-complex polypeptide 1 subunit 4; chaperonin containing t-complex polypeptide 1, delta subunit; chaperonin containing TCP1, subunit 4 (delta); chaperonin subunit 4 (delta); Stimulator of TAR RNA-binding; T complex protein 1, delta; T-complex protein 1 subunit delta; TCP-1 delta; TCP-1-delta
基因别名: 2610204B21Rik; A45; C78323; CCT-DELTA; CCT4; CCTD; SRB
UniProt ID: (Human) P50991, (Mouse) P80315
Entrez Gene ID: (Rabbit) 100353000, (Human) 10575, (Pig) 100521551, (Mouse) 12464
protein folding
binding of sperm to zona pellucida
positive regulation of telomere maintenance via telomerase
protein stabilization
positive regulation of telomerase activity
scaRNA localization to Cajal body
toxin transport
positive regulation of establishment of protein localization to telomere
positive regulation of protein localization to Cajal body
positive regulation of telomerase RNA localization to Cajal body
