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Invitrogen
ThPOK Recombinant Rat Monoclonal Antibody (2POK)
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ThPOK Antibody (740260T) in IHC (P)
Immunohistochemical analysis of ThPOK was performed using formalin-fixed paraffin-embedded mouse skin tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - High pH (10X) (Product # 00-4956-58) diluted to 1X solution in water in a decloaking chamber at 110°C for 15 min. Following antigen retr... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
740260T
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2a, kappa
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
2POK
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2-7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
Recombinant rat monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency.
It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Target Information
ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g., COL1A1; MIM 120150) and has a role in development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp686G01254; krueppel-related zinc finger protein cKrox; RP11-307C12.9; T-helper-inducing POZ/Krueppel-like factor; unnamed protein product; Vzinc finger and BTB domain containing 7B; zinc finger protein 67; zinc finger protein Th-POK
Gene Aliases: c-Krox; Thpok; Zfp67
UniProt ID: (Mouse) Q64321
Entrez Gene ID: (Mouse) 22724
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
protein homodimerization activity
histone deacetylase binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
NK T cell differentiation
regulation of transcription from RNA polymerase II promoter
lactation
regulation of gene expression
positive regulation of gene expression
negative regulation of gene expression
positive regulation of interleukin-17 production
response to insulin
regulation of CD4-positive, alpha-beta T cell differentiation
positive regulation of CD4-positive, alpha-beta T cell differentiation
regulation of CD8-positive, alpha-beta T cell differentiation
negative regulation of CD8-positive, alpha-beta T cell differentiation
positive regulation of fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of insulin receptor signaling pathway
negative regulation of NK T cell proliferation
positive regulation of brown fat cell differentiation
positive regulation of cold-induced thermogenesis
adaptive thermogenesis
negative regulation of T-helper 17 cell differentiation
positive regulation of SREBP signaling pathway
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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