Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Antibodies Inc
Kv4.2 K+ Channel Monoclonal Antibody (K57/1), FL594
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
75-016-FL594
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
K57/1
Immunogen
Synthetic peptide amino acids 209 -225 (extracellular S1-S2 loop) of rat Kv4.2 (CGSSPGHIKELPSGERY; accession number Q63881).
Conjugate
Excitation/Emission Max
594/615 nm
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes-shaker, shaw, shab, and shal-have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: A-type voltage-gated potassium channel KCND2; potassium channel Kv4.2; potassium channel, voltage gated Shal related subfamily D, member 2; potassium voltage gated channel, Shal-related family, member 2; Potassium voltage-gated channel subfamily D member 2; potassium voltage-gated channel, Shal-related subfamily, member 2; RK5; Shal1; Voltage-gated potassium channel subunit Kv4.2; voltage-sensitive potassium channel
Gene Aliases: AI839615; AW555701; KCND2; KIAA1044; KV4.2; mKIAA1044; MNCb-7013; R75121; RK5; Shal1
UniProt ID: (Human) Q9NZV8, (Rat) Q63881, (Mouse) Q9Z0V2
Entrez Gene ID: (Human) 3751, (Rat) 65180, (Mouse) 16508
voltage-gated potassium channel activity
A-type (transient outward) potassium channel activity
delayed rectifier potassium channel activity
protein binding
metal ion binding
ion channel activity
potassium channel activity
protein heterodimerization activity
voltage-gated ion channel activity
voltage-gated ion channel
action potential
chemical synaptic transmission
neuronal action potential
sensory perception of pain
regulation of ion transmembrane transport
locomotor rhythm
protein homooligomerization
cardiac conduction
cellular response to hypoxia
potassium ion transmembrane transport
potassium ion transport
cellular response to drug
protein heterooligomerization
cellular response to mechanical stimulus
cardiac muscle cell action potential
transport
ion transport
transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support