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Antibodies Inc
Snapin/SNAPAP Monoclonal Antibody (L8/15)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
75-045
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
L8/15
抗原
Synthetic peptide of amino acids 115-136 of human snapin (KETARRRAMLDSGIYPPGSPGK; accession number Q95295).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 7.4
内含物
0.065% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: biogenesis of lysosomal organelles complex-1, subunit 7; Biogenesis of lysosome-related organelles complex 1 subunit 7; BLOC-1 related complex subunit 3; BLOC-1 subunit 7; SNAP-25-binding protein; SNAP-associated protein; SNARE associated protein snapin; SNARE-associated protein; SNARE-associated protein Snapin; synaptosomal-associated protein 25 binding protein; Synaptosomal-associated protein 25-binding protein; synaptosomal-associated protein, 25 kDa, binding protein; unnamed protein product
基因别名: 25kDa; AA407989; AV026596; BLOC1S7; BLOS7; BORCS3; SNAP25BP; SNAPAP; SNAPIN
UniProt ID: (Human) O95295, (Mouse) Q9Z266, (Rat) P60192
Entrez Gene ID: (Human) 23557, (Mouse) 20615, (Rat) 295217
intracellular protein transport
exocytosis
lysosome organization
lysosomal lumen acidification
chemical synaptic transmission
neurotransmitter secretion
anterograde axonal transport
retrograde axonal transport
endosome to lysosome transport
negative regulation of neuron projection development
synaptic vesicle exocytosis
synaptic vesicle maturation
neuron projection development
protein complex localization
synaptic vesicle fusion to presynaptic active zone membrane
lysosome localization
melanosome organization
synaptic vesicle transport
anterograde synaptic vesicle transport
regulation of endosome size
protein maturation
establishment of vesicle localization
regulation of lysosome size
neuron cellular homeostasis
organelle transport along microtubule
terminal button organization
autophagosome maturation
late endosome to lysosome transport
positive regulation of late endosome to lysosome transport
regulation of synaptic vesicle exocytosis
calcium ion regulated exocytosis
regulation of protein binding
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