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Antibodies Inc
NGL-3/LRRC4B Monoclonal Antibody (N51/6), FL490
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产品信息
75-085-FL490
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
N51/6
抗原
Fusion protein amino acids 598-709 of rat NGL-3 (Leucine-rich repeat-containing 4B protein (Lrrc4B), accession number XP_218615) produced recombinantly in E. Coli.
偶联物
激发/发射光谱
491/515 nm
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
The LRRC4B gene encodes a protein known as leucine-rich repeat-containing protein 4B, which is involved in cellular signaling and neural development. LRRC4B is a member of the leucine-rich repeat (LRR) protein family, characterized by its ability to mediate protein-protein interactions through its LRR domains. This protein is predominantly expressed in the nervous system and plays a crucial role in neuronal growth, synapse formation, and signal transduction pathways essential for brain development and function. LRRC4B contributes to cell adhesion, growth cone guidance, and synaptic plasticity, influencing the formation and maintenance of neural circuits. Its dysregulation has been linked to neurodevelopmental disorders, highlighting its importance in cognitive functions and neurological health. Additionally, LRRC4B is implicated in cancer biology, where it may act as a tumor suppressor, modulating cellular proliferation and migration. Research continues to explore LRRC4B's interactions and regulatory mechanisms, offering insights into potential therapeutic applications for neurological diseases and cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Leucine-rich repeat-containing protein 4B; leucine-rich repeats and immunoglobulin-like domains 4; Netrin-G3 ligand; NGL-3; protein NGL-3
基因别名: A830007M12; Lrig4; Lrrc4b; NGL-3
UniProt ID: (Rat) P0CC10, (Mouse) P0C192
Entrez Gene ID: (Rat) 308571, (Mouse) 272381
