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Antibodies Inc
QKI-6 Monoclonal Antibody (N182/17)
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Product Details
75-190
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
N182/17
Immunogen
Synthetic peptide amino acids 329-341 of human QKI-6 (accession number Q96PU8-2).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4
Contains
0.065% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Sequence of this protein is as follows: PSGVLGMAFP TKG
Target Information
QKI-6 is an isoform of the RNA-binding protein QKI (Quaking), which plays a crucial role in the regulation of RNA splicing, stability, and translation. This protein is particularly important for the development and maintenance of the nervous system, including the formation and maintenance of myelin sheaths around nerve fibers. Dysregulation or mutations in QKI-6 have been associated with various neurological disorders, such as schizophrenia and demyelinating diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homolog of mouse quaking QKI (KH domain RNA binding protein); Hqk; KH domain-containing RNA-binding protein QKI; lethal, Chr 17, U Wisconsin 1; MqkI; Protein quaking; QKI, KH domain containing, RNA binding; QKI-5 protein; quaking homolog, KH domain RNA binding; RNA binding protein HQK
Gene Aliases: 1110003F05Rik; 1500005P18; HKQ; Hqk; hqkI; l(17)-1Wis; l17Wis1; QK; QK1; QK3; QKI
UniProt ID: (Human) Q96PU8, (Mouse) Q9QYS9
Entrez Gene ID: (Human) 9444, (Mouse) 19317
vasculogenesis
mRNA processing
spermatid development
RNA splicing
positive regulation of gene expression
myelination
muscle cell differentiation
long-chain fatty acid biosynthetic process
mRNA transport
3'-UTR-mediated mRNA destabilization
regulation of translation
transport
multicellular organism development
axon ensheathment
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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