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TARPGamma2/Stargazin Monoclonal Antibody (N245/1)
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产品信息
75-242
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
N245/1
抗原
Fusion protein amino acids 203-323 (cytoplasmic C-terminus) of rat TARPGamma2 (accession number Q71RJ2) produced recombinantly in E. Coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 7.4
内含物
0.065% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium channel, voltage-dependent, gamma subunit 2; CaV gamma 2; MGC123981; MGC138502; MGC138504; neuronal voltage-gated calcium channel gamma-2 subunit; regulatory subunit; stargazin; TARP; TARP gamma-2; transmembrane AMPAR regulatory protein gamma-2; unnamed protein product
基因别名: B230105C07Rik; B930041E13Rik; Ipr328; stargazer; stargazin; stg; wag; waggler
UniProt ID: (Mouse) O88602, (Rat) Q71RJ2
Entrez Gene ID: (Mouse) 12300, (Rat) 84347
protein targeting to membrane
calcium ion transport
neuromuscular junction development
transmission of nerve impulse
regulation of membrane potential
neurological system process
response to calcium ion
membrane depolarization
positive regulation of synaptic transmission, glutamatergic
membrane hyperpolarization
eye blink reflex
calcium ion transmembrane transport
postsynaptic neurotransmitter receptor diffusion trapping
regulation of postsynaptic membrane neurotransmitter receptor levels
neurotransmitter receptor localization to postsynaptic specialization membrane
positive regulation of protein localization to basolateral plasma membrane
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
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