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Antibodies Inc
TARPGamma2/4/8 Monoclonal Antibody (N245/36), FL550
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产品信息
75-252-FL550
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
N245/36
抗原
Fusion protein amino acids 203-323 (cytoplasmic C-terminus) of rat TARPGamma2 (accession number Q71RJ2) produced recombinantly in E. Coli.
偶联物
FL550
FL550
FL550
激发/发射光谱
550/575 nm
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
Voltage-dependent calcium channel gamma-2 subunit, TARPGamma2 or Stargazin is encoded by the gene CACNG2 and is the transmembrane gamma subunit of the L-type calcium channel. Stargazin is in involved in regulation and trafficking of the ligand gated ion channel AMPA receptors. It is thought to play a role in learning and memory. Diseases associated with this gene include forms of deafness, Mental Retardation and childhood absnce epilepsy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium channel, voltage-dependent, gamma subunit 2; calcium channel, voltage-dependent, gamma subunit 4; calcium channel, voltage-dependent, gamma subunit 8; neuronal voltage-gated calcium channel gamma-2 subunit; neuronal voltage-gated calcium channel gamma-4 subunit; neuronal voltage-gated calcium channel gamma-8 subunit; regulatory subunit; stargazin; TARP gamma-2; TARP gamma-4; TARP gamma-8; transmembrane AMPAR regulatory protein gamma-2; transmembrane AMPAR regulatory protein gamma-4; transmembrane AMPAR regulatory protein gamma-8; unnamed protein product
基因别名: B230105C07Rik; B930041E13Rik; Ipr328; stargazer; stargazin; stg; wag; waggler
UniProt ID: (Mouse) O88602, (Rat) Q71RJ2, (Rat) Q8VHW9, (Mouse) Q9JJV4, (Rat) Q8VHW5
Entrez Gene ID: (Mouse) 12300, (Rat) 84347, (Rat) 140725, (Mouse) 54377, (Mouse) 81905, (Rat) 140729
calcium ion transport
transmission of nerve impulse
positive regulation of insulin secretion involved in cellular response to glucose stimulus
response to cocaine
positive regulation of synaptic transmission, glutamatergic
calcium ion transmembrane transport
postsynaptic neurotransmitter receptor diffusion trapping
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
protein targeting to membrane
neuromuscular junction development
regulation of membrane potential
neurological system process
response to calcium ion
membrane depolarization
membrane hyperpolarization
eye blink reflex
regulation of postsynaptic membrane neurotransmitter receptor levels
neurotransmitter receptor localization to postsynaptic specialization membrane
positive regulation of protein localization to basolateral plasma membrane
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