Search
Antibodies Inc
TASK1 Potassium Channel Monoclonal Antibody (N374/48), FL594
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
75-357-FL594
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
N374/48
Immunogen
Fusion protein amino acids 251-411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1 (accession number O54192) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
594/615 nm
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
KCNK3 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The gene product is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Acid-sensitive potassium channel protein TASK-1; Cardiac two pore background K(+) channel; cTBAK 1; cTBAK-1; KCNK9; Potassium channel subfamily K member 3; potassium channel, subfamily K, member 3; TASK 1; TWIK-related acid-sensitive K(+) channel 1; TWIK-related acid-sensitive K+ channel; Two pore K(+) channel KT3.1; Two pore potassium channel KT3.1
Gene Aliases: Ctbak; cTBAK-1; Kcnk3; rTASK; TASK; Task-1; Task1
UniProt ID: (Rat) O54912, (Mouse) O35111
Entrez Gene ID: (Rat) 29553, (Mouse) 16527
ion channel activity
open rectifier potassium channel activity
protein binding
protein C-terminus binding
potassium ion leak channel activity
protein homodimerization activity
S100 protein binding
protein heterodimerization activity
voltage-gated ion channel activity
potassium channel activity
ion channel
transporter
brain development
ion transmembrane transport
regulation of ion transmembrane transport
response to drug
negative regulation of cytosolic calcium ion concentration
cellular response to zinc ion
cellular response to hypoxia
potassium ion transmembrane transport
cochlea development
transport
ion transport
potassium ion transport
stabilization of membrane potential
mitophagy in response to mitochondrial depolarization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support