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Npas4 Monoclonal Antibody (N408/79)
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FIGURE: 1 / 3
Npas4 Antibody (75-396) in IHC (F)
Immunoblot against crude brain low-speed pellets from untreated adult rats (RBLSP), adult rats treated with kainic acid to induce seizures (RBLSP seiz) and adult rats treated with saline (RBLSP non-seiz) probed with N408/79 (left) and N52A/42 (right) TC supe and with Rabbit anti-c-Fos (middle).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
75-396
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
N408/79
Immunogen
Fusion protein amino acids 597-802 (C-terminus) of rat Npas4 (accession number Q8CJH6) produced recombinantly in E. Coli.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4
Contains
0.065% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bHLH PAS type transcription factor NXF; bHLH-PAS type transcription factor NXF; HLH-PAS transcription factor NXF; LE-PAS; Limbic-enhanced PAS protein; Neuronal PAS domain-containing protein 4; Neuronal PAS4; PASD10 and LE-PAS
Gene Aliases: LE-PAS; Npas4; Nxf
UniProt ID: (Rat) Q8CJH6, (Mouse) Q8BGD7
Entrez Gene ID: (Rat) 266734, (Mouse) 225872
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II regulatory region DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
signal transducer activity
protein heterodimerization activity
RNA polymerase II transcription factor activity, sequence-specific DNA binding
protein dimerization activity
basic helix-loop-helix transcription factor
transcription, DNA-templated
signal transduction
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
inhibitory postsynaptic potential
cellular response to corticosterone stimulus
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
cellular response to stress
cellular response to acid chemical
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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