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Antibodies Inc
Celf4/Brunol4 Monoclonal Antibody (N446/80), FL650
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Product Details
75-438-FL650
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
N446/80
Immunogen
Fusion protein amino acids 2-87 (N-terminus) of human Celf4 (accession number Q9BZC1) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
655/676 nm
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bruno -like 4; bruno-like 4, RNA binding protein; Bruno-like protein 4; CELF-4; CUG-BP- and ETR-3-like factor 4; CUGBP; CUGBP Elav-like family member 4; LYST-interacting protein LIP9; RNA-binding protein; RNA-binding protein BRUNOL-4; RNA-binding protein BRUNOL4; unnamed protein product
Gene Aliases: A230070D14Rik; Brul4; BRUNOL-4; BRUNOL4; C130060B05Rik; CELF-4; CELF4
UniProt ID: (Human) Q9BZC1, (Mouse) Q7TSY6
Entrez Gene ID: (Human) 56853, (Rat) 307540, (Mouse) 108013
alternative mRNA splicing, via spliceosome
regulation of alternative mRNA splicing, via spliceosome
mRNA splice site selection
negative regulation of mRNA splicing, via spliceosome
positive regulation of mRNA splicing, via spliceosome
negative regulation of excitatory postsynaptic potential
mRNA splicing, via spliceosome
in utero embryonic development
mRNA processing
germ cell development
RNA splicing
embryo development ending in birth or egg hatching
negative regulation of translation
excitatory postsynaptic potential
regulation of retina development in camera-type eye
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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