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In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant mouse A33 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cell surface A33 antigen; Glycoprotein A33; glycoprotein A33 (transmembrane); MGC129986; MGC129987; transmembrane glycoprotein A33
基因别名: A33; GPA33
UniProt ID: (Human) Q99795
Entrez Gene ID: (Human) 10223