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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The ATP-binding cassette (ABC) superfamily is comprised of transmembrane proteins involved in energy-dependent transport of a variety of substrates across membranes. ABCA6 is a 1,617 amino acid protein belonging to the ABC transporter family. ABCA6 is up-regulated during monocyte differentiation into macrophages, suggesting a role in macrophage lipid homeostasis. ABCA6 contains two ABC transporter domains and is expressed as three isoforms produced by alternative splicing. ABCA6 is present at highest levels in adult liver, with significant levels found in many adult tissues and fetal lung, kidney and liver.
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蛋白别名: ABC transporter ABCA6; ATP-binding cassette A6; ATP-binding cassette sub-family A member 6; ATP-binding cassette transporter sub-family A member 6; ATP-binding cassette, sub-family A (ABC1), member 6; ATP-binding cassette, subfamily A (ABC1), member 6
基因别名: 6330565N06Rik; ABCA6; EST155051
UniProt ID: (Human) Q8N139, (Mouse) Q8K441
Entrez Gene ID: (Human) 23460, (Mouse) 76184, (Rat) 303639
分子生物学功能: ATP-binding cassette (ABC) transporter primary active transporter transporter