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Invitrogen
ABCC6 Polyclonal Antibody
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ABCC6 Antibody (PA5-103933) in IHC (P)
Immunohistochemistry analysis of ABCC6 in mouse kidney tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with ABCC6 polyclonal antibody (Product # PA5-103933) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-103933
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ABCC6(Accession O95255), corresponding to amino acid residues L316-F366.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total MRP6.
靶标信息
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: anthracycline resistance-associated protein; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; ATP-binding cassette, subfamily C (CFTR/MRP), member 6; liver multidrug resistance-associated protein 6; MLP-1; MOAT-E; MRP-like protein 1; MRP6; CFTR/MRP; member of the ATP-binding cassette (ABC) transporters; multi-specific organic anion transporter E; multidrug resistance-associated protein 6; similar to multidrug resistance protein MRP1; unnamed protein product
基因别名: ABC34; Abcc1b; ARA; DCC; dyscalc; Dyscalc1; EST349056; GACI2; MLP1; MOAT-E; MOATE; MRP6; PXE; PXE1; URG7
UniProt ID: (Human) O95255, (Mouse) Q9R1S7, (Rat) O88269
Entrez Gene ID: (Human) 368, (Mouse) 27421, (Rat) 81642
drug transmembrane transport
gene expression
ATP transport
inorganic diphosphate transport
cellular phosphate ion homeostasis
response to magnesium ion
ATP metabolic process
phosphate ion homeostasis
calcium ion homeostasis
transmembrane transport
leukotriene transport
inhibition of non-skeletal tissue mineralization
response to sodium phosphate
response to xenobiotic stimulus
carboxylic acid transport
biological_process
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