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Invitrogen
ABCD2 Polyclonal Antibody
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Product Details
PA5-42397
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human ABCD2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: WRFEQLDTAI RLTLSEEKQK LESQLAGIPK MQQRLNELCK ILGEDSVLKT
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 85%; Zebrafish: 79%
Target Information
ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adrenoleukodystrophy-like 1; Adrenoleukodystrophy-related protein; ATP-binding cassette sub-family D member 2; ATP-binding cassette, sub-family D (ALD), member 2; hALDR; unnamed protein product
Gene Aliases: ABC39; ABCD2; ALD1; ALDL1; ALDR; ALDRP; hALDR
UniProt ID: (Human) Q9UBJ2
Entrez Gene ID: (Human) 225
nucleotide binding
long-chain fatty acid transporter activity
protein binding
ATP binding
organophosphate ester transmembrane transporter activity
nucleobase-containing compound transmembrane transporter activity
hydrolase activity
ATPase activity
ATPase activity, coupled to transmembrane movement of substances
protein homodimerization activity
amide transmembrane transporter activity
protein heterodimerization activity
acyl-CoA hydrolase activity
ABC-type transporter activity
sulfur compound transmembrane transporter activity
very long-chain fatty acid metabolic process
fatty acid biosynthetic process
fatty acid beta-oxidation
unsaturated fatty acid biosynthetic process
peroxisome organization
response to bacterium
organophosphate ester transport
peroxisomal long-chain fatty acid import
nucleobase-containing compound transport
regulation of fatty acid metabolic process
positive regulation of fatty acid beta-oxidation
alpha-linolenic acid metabolic process
long-chain fatty acid biosynthetic process
very long-chain fatty acid catabolic process
amide transport
myelin maintenance
linoleic acid metabolic process
transmembrane transport
negative regulation of cytokine production involved in inflammatory response
fatty acid derivative biosynthetic process
negative regulation of reactive oxygen species biosynthetic process
neuron projection maintenance
positive regulation of unsaturated fatty acid biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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