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Abnova
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAELQMLLEE EIPGGRRALF DSYTNLERVA DYCENNYIQS ADKQRALEET KAYTTQSLAS VAYLINTLAN NVLQMLDIQA SQLRRMESSI NHISQTVDIH KEKVARREIG ILTTNKNTSR THKIIAPANL ERPVRYIRKP IDYTILDDIG HGVKVSTQNM KMGGLPRTTP PTQKPPSPPM SGKGTLGRHS PYRTLEPVRP PVVPNDYVPS PTRNMAPSQQ SPVRTASVNQ RNRTYSSSGS SGGSHPSSRS SSRENSGSGS VGVPIAVPTP SPPSVFPGHP VQFYSMNRPA SRHTPPTIGG SLPYRRPPSI TSQTSLQNQM NGGPFYSQNP VSLAPPPPSI LQVTPQLPLM GFVARVQENI SDTPPPPPPV EEPVFDESPP PPPPPEDYEE EEAAVVEYSD PYAEEDPPWA PRSYLEKVVA IYDYTKDKED ELSFQEGAII YVIKKNDDGW YEGVMNGVTG LFPGNYVESI MHYSE
ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Abelson interactor 2; Abi-2; Abl interactor 2; Abl-binding protein 3; AblBP3; Arg-binding protein 1; ArgBP1
基因别名: ABI2; ARGBPIA
Entrez Gene ID: (Human) 10152