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Invitrogen
ABI2 Polyclonal Antibody
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ABI2 Antibody (PA5-95121) in WB
Western blot analysis of ABI2 in, Lane 1: human 293T whole cell lysates, Lane 2: human Hela whole cell lysates, Lane 3: human K562 whole cell lysates, Lane 4: human SH-SY5Y whole cell lysates, Lane 5: rat brain tissue lysates, Lane 6: rat PC-12 whole cell lysates, Lane 7: mouse brain tissue lysates. Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 µg of sample under reducing conditions. After Electrophoresis, proteins were transf... View More
产品信息
PA5-95121
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human ABI2 (158-173aa RFKVSTQNMKMGGLPR).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human 293T whole cell, human Hela whole cell, human K562 whole cell, human SH-SY5Y whole cell, rat brain tissue, rat PC-12 whole cell, mouse brain tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Abelson interactor 2; Abi-2; abl binding protein 3; Abl interactor 2; Abl-binding protein 3; abl-interacting protein 1 (SH3-containing protein); abl-interactor protein 2b; AblBP3; arg protein tyrosine kinase-binding protein; Arg-binding protein 1; ArgBP1; thyroid hormone responsive protein
基因别名: 8430425M24Rik; ABI-2; ABI2; ABI2B; AblBP3; AI839867; AIP-1; argBP1; ARGBPIA; argBPIB; C130078H13; SSH3BP2
UniProt ID: (Human) Q9NYB9, (Mouse) P62484
Entrez Gene ID: (Human) 10152, (Mouse) 329165, (Rat) 286928
movement of cell or subcellular component
cytoskeleton organization
actin polymerization or depolymerization
viral process
cell migration
Rac protein signal transduction
peptidyl-tyrosine phosphorylation
positive regulation of Arp2/3 complex-mediated actin nucleation
learning or memory
dendrite development
camera-type eye development
